Note Iago's crass comments that center around interracial marriage.
As above noted, Iago speaks of Othello with grotesque animal imagery.
In the first scene of the play, Othello is called to wage war against Cyprus (I.iii).
In war he is known as a man of duty, service and confident leadership.
Desdemona, then exists as a poignant statement against the masculine principle and patriarchy.
Even Iago's diabolically convincing words could not have replaced Othello's loyalty and faith in his beloved Desdemona.
Othello is repeatedly characterized by the nature of his skin.
In the first scene of Othello Iago hisses to Barbantio, Desdemona's father, that ' an old black ram/ Is tupping your white ewe (I.i. Continuing, Iago calls Othello a 'Barbary Horse' (I.i.122).
The motif of racial prejudice cannot go ignored in Othello.
It would be difficult to imagine that the crowds that gathered to watch were neutral to the topic of race given the historical context.